Ifn-alpha protein
WebUniProt Summary. FUNCTION: SwissProt: P01563 # Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. SIZE: 188 amino acids; 21550 Da. SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P01563 ## Belongs to … WebHuman Interferon-alpha 2a produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The …
Ifn-alpha protein
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WebHuman interferon alpha (hIFNα) is a wide biological activity cytokine that is used in hepatitis and cancer treatments. It regulates many genes that are involved in antiviral … The mammalian types are designated IFN-α (alpha), IFN-β (beta), IFN-κ (kappa), IFN-δ (delta), IFN-ε (epsilon), IFN-τ (tau), IFN-ω (omega), and IFN-ζ (zeta, also known as limitin). Of these types, IFN-α, IFN -ω, and IFN-τ can work across species. The IFN-α proteins are produced mainly by plasmacytoid dendritic cells (pDCs). They are mainly involved in innate immunity against viral infection. The genes responsible for their synthesis co…
Web8 jan. 2024 · In a recent issue of the Journal of Experimental Medicine, Zhang et al. reported that type I interferon (type I IFN) signaling mediates Mycobacterium tuberculosis (Mtb)-induced macrophage (MΦ)... WebRecombinant human Interferon alpha 1 protein (Active) Interferon alpha 1 タンパク質・ペプチド 製品一覧 生理活性 Interferon alpha 1 (ab48750) has the activity of 4 X 10 5 unit/mg (or 4 X 10 5 unit/ml). This activity has been tested by evaluating anti-proliferation with Daudi cells. For Further information see Kim et al., 2009. 精製度 > 95 % SDS-PAGE.
Web1 sep. 2004 · We have produced prolonged, high local concentrations of interferon in vivo by intravesical instillation of adenoviruses encoding interferon-α (Ad-IFNα) together with the gene transfer-enhancing agent Syn3. We found sustained interferon protein levels for days, both in normal mouse urothelium and in human bladder cancer cells growing as … Web21 mrt. 2003 · The Vero cells are known to be defective in IFN synthesis; therefore, our data here indicate that the C terminus of the NDV V protein functions as an IFN-α antagonist in part by degrading the STAT1 protein. To test whether the expression of the V protein directly degrades the STAT1 protein, we carried out transfection experiments.
WebInterferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology.
WebIFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN … divorce lawyers in san antonio texasWeb5 nov. 2024 · TAK-573 is a first-in-class, humanized, anti-CD38, IgG4 monoclonal antibody genetically fused to 2 attenuated interferon alpha-2b (IFNα2b) molecules. The … divorce lawyers in silver city nmWebHowever, these cytokines (known as IFN-lambda1, 2, and 3) signal through a distinct receptor, and thus may be resistant to the evasion strategies used by some viruses to avoid the IFN-alpha/beta response. Orthopoxviruses are highly resistant to IFN-alpha/beta because they encode well-characterized immunomodulatory proteins that inhibit IFN ... craftsman riding lawn mower wheel bushingWebHuman Interferon-alpha 2a produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The Interferon-a 2a gene was obtained from human leukocytes. The rHuIFN-a 2a is purified by proprietary chromatographic techniques. 仅用于科研。 不用于诊断过程。 未经明确授权 … divorce lawyers in smyrna gaWebType I interferons (IFNs), IFN-alpha, IFN-beta, IFN-omega, IFN-delta and IFN-tau are a family of structurally related, species-specific proteins found only in vertebrates. They … divorce lawyers in stafford virginiaWebIFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. divorce lawyers in sioux fallsWeb30 sep. 2024 · Interferon alpha-inducible protein 27 (IFI27) is a hydrophobic mitochondrial protein composed of 122 amino acids [Citation 6]. Studies have … divorce lawyers in st. croix usvi